Ontology highlight
ABSTRACT:
SUBMITTER: Civra A
PROVIDER: S-EPMC7126780 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Civra Andrea A Colzani Mara M Cagno Valeria V Francese Rachele R Leoni Valerio V Aldini Giancarlo G Lembo David D Poli Giuseppe G
Free radical biology & medicine 20190913
Physiological cholesterol metabolism implies the generation of a series of oxidized derivatives, whose oxysterols are by far the most investigated ones for their potential multifaceted involvement in human pathophysiology. In this regard, noteworthy is the broad antiviral activity displayed by defined side chain oxysterols, in particular 25-hydroxycholesterol (25HC) and 27-hydroxycholesterol (27HC). Although their antiviral mechanism(s) may vary depending on virus/host interaction, these oxyster ...[more]