Ontology highlight
ABSTRACT:
SUBMITTER: Powell F
PROVIDER: S-EPMC7127247 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Powell Fiona F Rothwell Lisa L Clarkson Michael M Kaiser Pete P
Veterinary immunology and immunopathology 20120330 1-2
The cDNAs of two turkey cytokines, interleukin (IL)-10 and IL-13, were cloned using oligonucleotide primers designed from their chicken orthologues. The coding regions of the chicken and turkey genes are highly conserved, with IL-10 and IL-13 exhibiting 94.1% and 90% nucleotide and 92% and 79.9% amino acid identity respectively. Both showed consistent mRNA expression in turkey lymphoid and gut tissues. Expression in non-lymphoid tissues was more variable but generally highest in the skin and tra ...[more]