Ontology highlight
ABSTRACT:
SUBMITTER: Kimura M
PROVIDER: S-EPMC7132199 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Kimura Masahiro M Horie Takahiro T Baba Osamu O Ide Yuya Y Tsuji Shuhei S Ruiz Rodriguez Randolph R Watanabe Toshimitsu T Yamasaki Tomohiro T Otani Chiharu C Xu Sijia S Miyasaka Yui Y Nakashima Yasuhiro Y Kimura Takeshi T Ono Koh K
EMBO reports 20200309 4
The Hippo signaling pathway is involved in the pathophysiology of various cardiovascular diseases. Yes-associated protein (YAP) and transcriptional enhancer activator domain (TEAD) transcriptional factors, the main transcriptional complex of the Hippo pathway, were recently identified as modulators of phenotypic switching of vascular smooth muscle cells (VSMCs). However, the intrinsic regulator of YAP/TEAD-mediated gene expressions involved in vascular pathophysiology remains to be elucidated. H ...[more]