Ontology highlight
ABSTRACT:
SUBMITTER: Fan X
PROVIDER: S-EPMC7132640 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Epigenomics 20190220 4
<h4>Aim</h4>A genomic region on 5q33.3 lies between and encompasses the IL12B and PTTG1 genes, and contains many potential psoriasis causal variants. We aimed to further examine the influence of variants in and around this region.<h4>Materials & methods</h4>We used least absolute shrinkage and selection operator (LASSO)-based regression analysis to assess independent contributions of 2171 variants to psoriasis susceptibility and tested them for association with different clinical psoriasis subty ...[more]