Ontology highlight
ABSTRACT:
SUBMITTER: Wang X
PROVIDER: S-EPMC7136926 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Wang Xiang X Yu Junyan J Yang Mudan M Liu Likun L Gao Jinghua J Ren Yuchuan Y Zhang Ruixing R Zhong Diansheng D Du Nan N Fu Zhanzhao Z Jia Junmei J Li Qingshan Q Diao Jianfeng J Zhang Junping J Guo Jun J Li Xiaomei X Song Xiang X Zhang Yan Y Yu Zhonghe Z Ma Liwen L Fan Zaiwen Z Liu Zheng Z Li Guozhong G Liang Feng F Wang Huaqing H Gao Yunge Y Yang Ping P Bai Chunmei C Zang Aimin A Ren Xiubao X
American journal of cancer research 20200301 3
Apatinib, a VEGFR2 receptor tyrosine kinase inhibitor, showed survival benefits in Asian patients with heavily pretreated advanced gastric cancer. However, the adverse event (AEs) profile of apatinib has limited its use. Dosing schedules are used to alleviate toxicities despite no supportive evidence. This study aimed to analyze the toxicity and effectiveness of apatinib alone, especially with different dosing strategies in advanced gastric cancer patients under a real-world setting. Data from t ...[more]