Intravitreal Aflibercept injection with Panretinal photocoagulation versus early Vitrectomy for diabetic vitreous hemorrhage: randomized clinical trial.

ABSTRACT: To compare efficacy and safety of intravitreal aflibercept (IVA) injection with panretinal photocoagulation (PRP) versus early vitrectomy for diabetic vitreous hemorrhage (VH). Prospective, randomized study that included 34 eyes with diabetic VH. They were divided into two groups, Group ? (17 eyes) received three successive IVA injections followed by PRP and group ?? (17 eyes) for whom early vitrectomy was done. Follow up was carried out after one, two, three, six and nine months. The primary outcome measure was change in the mean best corrected visual acuity (BCVA) after nine months, secondary outcome measures were mean duration of clearance of VH and rate of recurrent hemorrhage with any additional treatment in both groups. Complications were reported. There was no statistically significant difference regarding initial demographic criteria between both groups. The mean final log MAR BCVA was statistically better than the initial BCVA in both groups (0.51?±?0.20, 1.17?±?0.48 for group I and 0.48?±?0.18, 1.44?±?0.44 for group II, P 

SUBMITTER: Abd Elhamid AH 

PROVIDER: S-EPMC7137269 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature