Ontology highlight
ABSTRACT:
SUBMITTER: Deymier AC
PROVIDER: S-EPMC7138367 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Deymier Alix C AC Schwartz Andrea G AG Lim Chanteak C Wingender Brian B Kotiya Akhilesh A Shen Hua H Silva Matthew J MJ Thomopoulos Stavros S
Bone 20191112
Despite a wealth of data on the effects of spaceflight on tendons and bones, little is known about its effects on the interfacial tissue between these two structures, the enthesis. Mice were sent to space on three separate missions: STS-131, STS-135, and Bion-M1 to determine how spaceflight affects the composition, structure, mechanics, and gene expression of the humerus-supraspinatus and calcaneus-Achilles entheses. At the nanoscale, spaceflight resulted in decreased carbonate levels in the bon ...[more]