Ontology highlight
ABSTRACT:
SUBMITTER: Kelly J
PROVIDER: S-EPMC7138567 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Kelly Jack J Moyeed Rana R Carroll Camille C Luo Shouqing S Li Xinzhong X
Aging 20200323 6
Parkinson's disease (PD) and Alzheimer's disease (AD) are the most common neurodegenerative diseases and there is increasing evidence that they share common physiological and pathological links. Here we have conducted the largest network analysis of PD and AD based on their gene expressions in blood to date. We identified modules that were not preserved between disease and healthy control (HC) networks, and important hub genes and transcription factors (TFs) in these modules. We highlighted that ...[more]