Ontology highlight
ABSTRACT:
SUBMITTER: Khan S
PROVIDER: S-EPMC7139844 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Khan Sabbir S Mittal Sandeep S McGee Kain K Alfaro-Munoz Kristin D KD Majd Nazanin N Balasubramaniyan Veerakumar V de Groot John F JF
International journal of molecular sciences 20200313 6
Recent efforts in brain tumor research have been directed towards the modulation of the immune system for therapeutic interventions. Several human cancers, including gliomas, are infiltrated with immune cell types-including neutrophils and myeloid-derived suppressor cells-that contribute to tumor progression, invasiveness, and treatment resistance. The role of tumor-associated neutrophils and myeloid-derived suppressor cells in cancer biology remains elusive, as these cells can exert a multitude ...[more]