Ontology highlight
ABSTRACT:
SUBMITTER: Ferreira AR
PROVIDER: S-EPMC7139948 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Ferreira Ana Rita AR Ramalho Ana Catarina AC Marques Mariana M Ribeiro Daniela D
Cancers 20200310 3
Human papillomaviruses (HPV) are the causative agents of the most common sexually transmitted infection worldwide. While infection is generally asymptomatic and can be cleared by the host immune system, when persistence occurs, HPV can become a risk factor for malignant transformation. Progression to cancer is actually an unintended consequence of the complex HPV life cycle. Different antiviral defence mechanisms recognize HPV early in infection, leading to the activation of the innate immune re ...[more]