Ontology highlight
ABSTRACT:
SUBMITTER: Pellegrini L
PROVIDER: S-EPMC7140035 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Pellegrini Laura L Sileno Sara S D'Agostino Marco M Foglio Eleonora E Florio Maria Cristina MC Guzzanti Vincenzo V Russo Matteo Antonio MA Limana Federica F Magenta Alessandra A
Cancers 20200317 3
Cancer treatment has made significant progress in the cure of different types of tumors. Nevertheless, its clinical use is limited by unwanted cardiotoxicity. Aside from the conventional chemotherapy approaches, even the most newly developed, i.e., molecularly targeted therapy and immunotherapy, exhibit a similar frequency and severity of toxicities that range from subclinical ventricular dysfunction to severe cardiomyopathy and, ultimately, congestive heart failure. Specific mechanisms leading ...[more]