Stress Erythropoiesis is a Key Inflammatory Response.
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ABSTRACT:
SUBMITTER: Paulson RF
PROVIDER: S-EPMC7140438 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
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Stress Erythropoiesis is a Key Inflammatory Response.
Paulson Robert F RF Ruan Baiye B Hao Siyang S Chen Yuanting Y
Cells 20200306 3
Bone marrow medullary erythropoiesis is primarily homeostatic. It produces new erythrocytes at a constant rate, which is balanced by the turnover of senescent erythrocytes by macrophages in the spleen. Despite the enormous capacity of the bone marrow to produce erythrocytes, there are times when it is unable to keep pace with erythroid demand. At these times stress erythropoiesis predominates. Stress erythropoiesis generates a large bolus of new erythrocytes to maintain homeostasis until steady ...[more]
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