Ontology highlight
ABSTRACT:
SUBMITTER: Uribe-Etxebarria V
PROVIDER: S-EPMC7140622 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Uribe-Etxebarria Verónica V García-Gallastegui Patricia P Pérez-Garrastachu Miguel M Casado-Andrés María M Irastorza Igor I Unda Fernando F Ibarretxe Gaskon G Subirán Nerea N
Cells 20200307 3
Dental pulp stem cells (DPSCs) from adult teeth show the expression of a very complete repertoire of stem pluripotency core factors and a high plasticity for cell reprogramming. Canonical Wnt and Notch signaling pathways regulate stemness and the expression of pluripotency core factors in DPSCs, and even very short-term (48 h) activations of the Wnt pathway induce a profound remodeling of DPSCs at the physiologic and metabolic levels. In this work, DPSC cultures were exposed to treatments modula ...[more]