Ontology highlight
ABSTRACT:
SUBMITTER: Lapitz A
PROVIDER: S-EPMC7140677 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Lapitz Ainhoa A Arbelaiz Ander A O'Rourke Colm J CJ Lavin Jose L JL Casta Adelaida La A Ibarra Cesar C Jimeno Juan P JP Santos-Laso Alvaro A Izquierdo-Sanchez Laura L Krawczyk Marcin M Perugorria Maria J MJ Jimenez-Aguero Raul R Sanchez-Campos Alberto A Riaño Ioana I Gónzalez Esperanza E Lammert Frank F Marzioni Marco M Macias Rocio I R RIR Marin Jose J G JJG Karlsen Tom H TH Bujanda Luis L Falcón-Pérez Juan M JM Andersen Jesper B JB Aransay Ana M AM Rodrigues Pedro M PM Banales Jesus M JM
Cells 20200314 3
<b>:</b> Cholangiocarcinoma (CCA) comprises a group of heterogeneous biliary cancers with dismal prognosis. The etiologies of most CCAs are unknown, but primary sclerosing cholangitis (PSC) is a risk factor. Non-invasive diagnosis of CCA is challenging and accurate biomarkers are lacking. We aimed to characterize the transcriptomic profile of serum and urine extracellular vesicles (EVs) from patients with CCA, PSC, ulcerative colitis (UC), and healthy individuals. Serum and urine EVs were isolat ...[more]