Ontology highlight
ABSTRACT:
SUBMITTER: Asrani S
PROVIDER: S-EPMC7140751 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Asrani Sanjay S Bacharach Jason J Holland Edward E McKee Hayley H Sheng Huan H Lewis Richard A RA Kopczynski Casey C CC Heah Theresa T
Advances in therapy 20200312 4
<h4>Introduction</h4>New open-angle glaucoma (OAG) and ocular hypertension (OHT) therapies that reduce treatment burden and improve outcomes relative to currently available agents are needed. Netarsudil, a novel Rho kinase inhibitor approved by the US Food and Drug Administration, reduces intraocular pressure (IOP) by increasing trabecular outflow. Two phase 3 superiority studies compared a fixed-dose combination (FDC) of netarsudil and the prostaglandin latanoprost with each active component fo ...[more]