Ontology highlight
ABSTRACT:
SUBMITTER: Chioccarelli T
PROVIDER: S-EPMC7141194 | biostudies-literature | 2020 Feb
REPOSITORIES: biostudies-literature
Chioccarelli Teresa T Pierantoni Riccardo R Manfrevola Francesco F Porreca Veronica V Fasano Silvia S Chianese Rosanna R Cobellis Gilda G
Journal of clinical medicine 20200227 3
Spermatozoa (SPZ) are motile cells, characterized by a cargo of epigenetic information including histone post-translational modifications (histone PTMs) and non-coding RNAs. Specific histone PTMs are present in developing germ cells, with a key role in spermatogenic events such as self-renewal and commitment of spermatogonia (SPG), meiotic recombination, nuclear condensation in spermatids (SPT). Nuclear condensation is related to chromatin remodeling events and requires a massive histone-to-prot ...[more]