Ontology highlight
ABSTRACT:
SUBMITTER: Fernandez-Nogueira P
PROVIDER: S-EPMC7141321 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Fernández-Nogueira Patricia P Mancino Mario M Fuster Gemma G Bragado Paloma P Puig Miquel Prats de MP Gascón Pere P Casado Francisco Javier FJ Carbó Neus N
Journal of clinical medicine 20200312 3
Current evidences state clear that both normal development of breast tissue as well as its malignant progression need many-sided local and systemic communications between epithelial cells and stromal components. During development, the stroma, through remarkably regulated contextual signals, affects the fate of the different mammary cells regarding their specification and differentiation. Likewise, the stroma can generate tumour environments that facilitate the neoplastic growth of the breast ca ...[more]