SimRVSequences: an R package to simulate genetic sequence data for pedigrees.
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ABSTRACT: Summary
We present the R package SimRVSequences to simulate sequence data for pedigrees. SimRVSequences allows for simulations of large numbers of single-nucleotide variants (SNVs) and scales well with increasing numbers of pedigrees. Users provide a sample of pedigrees and SNV data from a sample of unrelated individuals.Availability and implementation
SimRVSequences is publicly-available on CRAN https://cran.r-project.org/web/packages/SimRVSequences/.Supplementary information
Supplementary data are available at Bioinformatics online.
SUBMITTER: Nieuwoudt C
PROVIDER: S-EPMC7141864 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Publications
SimRVSequences: an R package to simulate genetic sequence data for pedigrees.
Nieuwoudt Christina C Brooks-Wilson Angela A Graham Jinko J
Bioinformatics (Oxford, England) 20200401 7
<h4>Summary</h4>We present the R package SimRVSequences to simulate sequence data for pedigrees. SimRVSequences allows for simulations of large numbers of single-nucleotide variants (SNVs) and scales well with increasing numbers of pedigrees. Users provide a sample of pedigrees and SNV data from a sample of unrelated individuals.<h4>Availability and implementation</h4>SimRVSequences is publicly-available on CRAN https://cran.r-project.org/web/packages/SimRVSequences/.<h4>Supplementary informatio ...[more]
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