Ontology highlight
ABSTRACT:
SUBMITTER: Liu D
PROVIDER: S-EPMC7142079 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Liu Dian D Ertay Ayse A Hill Charlotte C Zhou Yilu Y Li Juanjuan J Zou Yanmei Y Qiu Hong H Yuan Xianglin X Ewing Rob M RM Lu Xin X Xiong Hua H Wang Yihua Y
Cell death & disease 20200408 4
The apoptosis-stimulating protein of p53 (ASPP) family of proteins can regulate apoptosis by interacting with the p53 family and have been identified to play an important role in cancer progression. Previously, we have demonstrated that ASPP2 downregulation can promote invasion and migration by controlling β-catenin-dependent regulation of ZEB1, however, the role of ASPP1 in colorectal cancer (CRC) remains unclear. We analyzed data from The Cancer Genome Atlas (TCGA) and coupled this to in vitro ...[more]