Ontology highlight
ABSTRACT:
SUBMITTER: Charbonneau MR
PROVIDER: S-EPMC7142098 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Charbonneau Mark R MR Isabella Vincent M VM Li Ning N Kurtz Caroline B CB
Nature communications 20200408 1
A complex interplay of metabolic and immunological mechanisms underlies many diseases that represent a substantial unmet medical need. There is an increasing appreciation of the role microbes play in human health and disease, and evidence is accumulating that a new class of live biotherapeutics comprised of engineered microbes could address specific mechanisms of disease. Using the tools of synthetic biology, nonpathogenic bacteria can be designed to sense and respond to environmental signals in ...[more]