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Skin transcriptome profiling of Changthangi goats highlights the relevance of genes involved in Pashmina production.


ABSTRACT: Pashmina, the world's finest natural fiber is derived from secondary hair follicles of Changthangi goats which are domesticated in Ladakh region of Jammu and Kashmir by nomadic pastoralists. Complex epithelial-mesenchymal interactions involving numerous signal molecules and signaling pathways govern hair follicle morphogenesis and mitosis across different species. The present study involved transcriptome profiling of skin from fiber type Changthangi goats and meat type Barbari goats to unravel gene networks and metabolic pathways that might contribute to Pashmina development. In Changthangi goats, 525 genes were expressed at significantly higher levels and 54 at significantly lower levels with fold change >2 (padj?

SUBMITTER: Ahlawat S 

PROVIDER: S-EPMC7142143 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature

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Skin transcriptome profiling of Changthangi goats highlights the relevance of genes involved in Pashmina production.

Ahlawat Sonika S   Arora Reena R   Sharma Rekha R   Sharma Upasna U   Kaur Mandeep M   Kumar Ashish A   Singh Karan Veer KV   Singh Manoj Kumar MK   Vijh Ramesh Kumar RK  

Scientific reports 20200408 1


Pashmina, the world's finest natural fiber is derived from secondary hair follicles of Changthangi goats which are domesticated in Ladakh region of Jammu and Kashmir by nomadic pastoralists. Complex epithelial-mesenchymal interactions involving numerous signal molecules and signaling pathways govern hair follicle morphogenesis and mitosis across different species. The present study involved transcriptome profiling of skin from fiber type Changthangi goats and meat type Barbari goats to unravel g  ...[more]

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