Dataset Information

Maximum Aerobic Function: Clinical Relevance, Physiological Underpinnings, and Practical Application.

ABSTRACT: The earliest humans relied on large quantities of metabolic energy from the oxidation of fatty acids to develop larger brains and bodies, prevent and reduce disease risk, extend longevity, in addition to other benefits. This was enabled through the consumption of a high fat and low-carbohydrate diet (LCD). Increased fat oxidation also supported daily bouts of prolonged, low-intensity, aerobic-based physical activity. Over the past 40-plus years, a clinical program has been developed to help people manage their lifestyles to promote increased fat oxidation as a means to improve various aspects of health and fitness that include reducing excess body fat, preventing disease, and optimizing human performance. This program is referred to as maximum aerobic function, and includes the practical application of a personalized exercise heart rate (HR) formula of low-to-moderate intensity associated with maximal fat oxidation (MFO), and without the need for laboratory evaluations. The relationship between exercise training at this HR and associated laboratory measures of MFO, health outcomes and athletic performance must be verified scientifically.

SUBMITTER: Maffetone P

PROVIDER: S-EPMC7142223 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Maximum Aerobic Function: Clinical Relevance, Physiological Underpinnings, and Practical Application.

Maffetone Philip P Laursen Paul B PB

Frontiers in physiology 20200402

The earliest humans relied on large quantities of metabolic energy from the oxidation of fatty acids to develop larger brains and bodies, prevent and reduce disease risk, extend longevity, in addition to other benefits. This was enabled through the consumption of a high fat and low-carbohydrate diet (LCD). Increased fat oxidation also supported daily bouts of prolonged, low-intensity, aerobic-based physical activity. Over the past 40-plus years, a clinical program has been developed to help peop ...[more]

PMID: 32300310

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Project description:Performance problems in applications should ideally be detected as soon as they occur, i.e., directly when the causing code modification is added to the code repository. To this end, complex and cost-intensive application benchmarks or lightweight but less relevant microbenchmarks can be added to existing build pipelines to ensure performance goals. In this paper, we show how the practical relevance of microbenchmark suites can be improved and verified based on the application flow during an application benchmark run. We propose an approach to determine the overlap of common function calls between application and microbenchmarks, describe a method which identifies redundant microbenchmarks, and present a recommendation algorithm which reveals relevant functions that are not covered by microbenchmarks yet. A microbenchmark suite optimized in this way can easily test all functions determined to be relevant by application benchmarks after every code change, thus, significantly reducing the risk of undetected performance problems. Our evaluation using two time series databases shows that, depending on the specific application scenario, application benchmarks cover different functions of the system under test. Their respective microbenchmark suites cover between 35.62% and 66.29% of the functions called during the application benchmark, offering substantial room for improvement. Through two use cases-removing redundancies in the microbenchmark suite and recommendation of yet uncovered functions-we decrease the total number of microbenchmarks and increase the practical relevance of both suites. Removing redundancies can significantly reduce the number of microbenchmarks (and thus the execution time as well) to ~10% and ~23% of the original microbenchmark suites, whereas recommendation identifies up to 26 and 14 newly, uncovered functions to benchmark to improve the relevance. By utilizing the differences and synergies of application benchmarks and microbenchmarks, our approach potentially enables effective software performance assurance with performance tests of multiple granularities.

Dataset Information

Maximum Aerobic Function: Clinical Relevance, Physiological Underpinnings, and Practical Application.

Publications

Maximum Aerobic Function: Clinical Relevance, Physiological Underpinnings, and Practical Application.

Similar Datasets

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