Ontology highlight
ABSTRACT:
SUBMITTER: Pandey PR
PROVIDER: S-EPMC7144931 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Pandey Poonam R PR Yang Jen-Hao JH Tsitsipatis Dimitrios D Panda Amaresh C AC Noh Ji Heon JH Kim Kyoung Mi KM Munk Rachel R Nicholson Thomas T Hanniford Douglas D Argibay Diana D Yang Xiaoling X Martindale Jennifer L JL Chang Ming-Wen MW Jones Simon W SW Hernando Eva E Sen Payel P De Supriyo S Abdelmohsen Kotb K Gorospe Myriam M
Nucleic acids research 20200401 7
By interacting with proteins and nucleic acids, the vast family of mammalian circRNAs is proposed to influence many biological processes. Here, RNA sequencing analysis of circRNAs differentially expressed during myogenesis revealed that circSamd4 expression increased robustly in mouse C2C12 myoblasts differentiating into myotubes. Moreover, silencing circSamd4, which is conserved between human and mouse, delayed myogenesis and lowered the expression of myogenic markers in cultured myoblasts from ...[more]