Ontology highlight
ABSTRACT:
SUBMITTER: Meszaros B
PROVIDER: S-EPMC7145634 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Mészáros Bálint B Erdős Gábor G Szabó Beáta B Schád Éva É Tantos Ágnes Á Abukhairan Rawan R Horváth Tamás T Murvai Nikoletta N Kovács Orsolya P OP Kovács Márton M Tosatto Silvio C E SCE Tompa Péter P Dosztányi Zsuzsanna Z Pancsa Rita R
Nucleic acids research 20200101 D1
Membraneless organelles (MOs) are dynamic liquid condensates that host a variety of specific cellular processes, such as ribosome biogenesis or RNA degradation. MOs form through liquid-liquid phase separation (LLPS), a process that relies on multivalent weak interactions of the constituent proteins and other macromolecules. Since the first discoveries of certain proteins being able to drive LLPS, it emerged as a general mechanism for the effective organization of cellular space that is exploited ...[more]