Ontology highlight
ABSTRACT:
SUBMITTER: Kautsar SA
PROVIDER: S-EPMC7145714 | biostudies-literature | 2020 Jan
REPOSITORIES: biostudies-literature
Kautsar Satria A SA Blin Kai K Shaw Simon S Navarro-Muñoz Jorge C JC Terlouw Barbara R BR van der Hooft Justin J J JJJ van Santen Jeffrey A JA Tracanna Vittorio V Suarez Duran Hernando G HG Pascal Andreu Victòria V Selem-Mojica Nelly N Alanjary Mohammad M Robinson Serina L SL Lund George G Epstein Samuel C SC Sisto Ashley C AC Charkoudian Louise K LK Collemare Jérôme J Linington Roger G RG Weber Tilmann T Medema Marnix H MH
Nucleic acids research 20200101 D1
Fueled by the explosion of (meta)genomic data, genome mining of specialized metabolites has become a major technology for drug discovery and studying microbiome ecology. In these efforts, computational tools like antiSMASH have played a central role through the analysis of Biosynthetic Gene Clusters (BGCs). Thousands of candidate BGCs from microbial genomes have been identified and stored in public databases. Interpreting the function and novelty of these predicted BGCs requires comparison with ...[more]