Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women.
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ABSTRACT:
SUBMITTER: Thaung Zaw JJ
PROVIDER: S-EPMC7146200 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
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Sustained Cerebrovascular and Cognitive Benefits of Resveratrol in Postmenopausal Women.
Thaung Zaw Jay Jay JJ Howe Peter R C PRC Wong Rachel H X RHX
Nutrients 20200320 3
Deficits in the cerebral microcirculation contribute to age-related cognitive decline. In a pilot study of postmenopausal women, we found that supplementation with a low dose of resveratrol, a phytoestrogen, for 14 weeks improved cerebrovascular and cognitive functions. We have since undertaken a larger, longer term study to confirm these benefits. Postmenopausal women aged 45-85 years (<i>n</i> = 129) were randomized to take placebo or 75 mg trans-resveratrol twice daily for 12 months. Effects ...[more]
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