Ontology highlight
ABSTRACT:
SUBMITTER: Campbell K
PROVIDER: S-EPMC7149230 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Campbell Kate K Westholm Jakub J Kasvandik Sergo S Di Bartolomeo Francesca F Mormino Maurizio M Nielsen Jens J
Proceedings of the National Academy of Sciences of the United States of America 20200325 14
For cells to replicate, a sufficient supply of biosynthetic precursors is needed, necessitating the concerted action of metabolism and protein synthesis during progressive phases of cell division. A global understanding of which biosynthetic processes are involved and how they are temporally regulated during replication is, however, currently lacking. Here, quantitative multiomics analysis is used to generate a holistic view of the eukaryal cell cycle, using the budding yeast <i>Saccharomyces ce ...[more]