GRB10 and E2F3 as Diagnostic Markers of Osteoarthritis and Their Correlation with Immune Infiltration.
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ABSTRACT:
SUBMITTER: Deng YJ
PROVIDER: S-EPMC7151213 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Publications
GRB10 and E2F3 as Diagnostic Markers of Osteoarthritis and Their Correlation with Immune Infiltration.
Deng Ya-Jun YJ Ren En-Hui EH Yuan Wen-Hua WH Zhang Guang-Zhi GZ Wu Zuo-Long ZL Xie Qi-Qi QQ
Diagnostics (Basel, Switzerland) 20200322 3
This study aimed to find potential diagnostic markers for osteoarthritis (OA) and analyze the role of immune cells infiltration in this pathology. We used OA datasets from the Gene Expression Omnibus database. First, R software was used to identify differentially expressed genes (DEGs) and perform functional correlation analysis. Then least absolute shrinkage and selection operator (LASSO) logistic regression and support vector machine-recursive feature elimination algorithms were used to screen ...[more]
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