Metals and trace elements in relation to body mass index in a prospective study of US women.

ABSTRACT:

Background

Epidemiologic studies on the association between metals and body mass index (BMI) have been cross-sectional and have demonstrated inconsistent associations. Our study prospectively examined whether metals measured at baseline were associated with later BMI. We considered metals individually and as joint exposure to pre-defined metal groupings.

Methods

We measured concentrations of 16 metals in toenails collected at baseline (2003-2009) in a subset of 1221 women from the Sister Study. We calculated BMI from height and weight reported on a follow-up questionnaire an average of 5.2 years (range = 3.5-8.3) after baseline. Multivariable linear regression was used to estimate β coefficients and 95% confidence intervals (CIs) for associations between BMI and individual m

SUBMITTER: Niehoff NM 

PROVIDER: S-EPMC7153007 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature