Ontology highlight
ABSTRACT:
SUBMITTER: Ballantyne CM
PROVIDER: S-EPMC7153222 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Ballantyne Christie M CM Laufs Ulrich U Ray Kausik K KK Leiter Lawrence A LA Bays Harold E HE Goldberg Anne C AC Stroes Erik Sg ES MacDougall Diane D Zhao Xin X Catapano Alberico L AL
European journal of preventive cardiology 20190729 6
<h4>Aims</h4>The aim of this study was to evaluate the low-density lipoprotein cholesterol lowering efficacy and safety of a bempedoic acid 180 mg and ezetimibe 10 mg fixed-dose combination in patients with hypercholesterolemia and a high risk of cardiovascular disease receiving maximally tolerated statin therapy.<h4>Methods</h4>This phase 3, double-blind clinical trial enrolled adult patients at high risk of cardiovascular disease due to atherosclerotic cardiovascular disease, heterozygous fami ...[more]