Ontology highlight
ABSTRACT:
SUBMITTER: Santos ES
PROVIDER: S-EPMC7154094 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Santos Emanuelle de Souza ES de Aragão-França Luciana Souza LS Meira Cássio Santana CS Cerqueira Jéssica Vieira JV Vasconcelos Juliana Fraga JF Nonaka Carolina Kymie Vasques CKV Pontes-de-Carvalho Lain Carlos LC Soares Milena Botelho Pereira MBP
Frontiers in immunology 20200407
Chronic Chagas disease cardiomyopathy (CCC) is the most frequent and severe form of this parasitic disease. CCC is caused by a progressive inflammation in the heart, resulting in alterations that can culminate in heart failure and death. The use of dendritic cells (DCs) appears as an option for the development of treatments due to their important role in regulating immune responses. Here, we investigated whether tolerogenic cells (tDCs) could interfere with the progression of CCC in an experimen ...[more]