Ultrasound-guided erector spinae plane block for postoperative analgesia: a meta-analysis of randomized controlled trials.

ABSTRACT: BACKGROUND:Ultrasound-guided Erector Spinae Plane Block (ESPB) has been increasingly applied in patients for postoperative analgesia. Its effectiveness remain uncertain. This meta-analysis aimed to determine the clinical efficacy of ultrasound-guided ESPB in adults undergoing general anesthesia (GA) surgeries. METHODS:A systematic databases search was conducted in PubMed, Embase, and the Cochrane Library for randomized controlled trials (RCTs) comparing ESPB with control or placebo. Primary outcome was iv. opioid consumption 24?h after surgery. Standardized mean differences (SMDs) and risk ratios (RRs) with 95% confidence intervals (CIs) were calculated with a random-effects model. RESULTS:A total of 12 RCTs consisting of 590 patients were included. Ultrasound-guided ESPB showed a reduction of intravenous opioid consumption 24?h after surgery (SMD?=?-?2.18; 95% confidence interval (CI) -2.76 to -?1.61,p?

SUBMITTER: Huang J 

PROVIDER: S-EPMC7155251 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature