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A Great Mimicker in Thoracic Spine: Spinal Double Expressor Lymphoma.


ABSTRACT: Diffuse large B-cell lymphoma (DLBCL) is one of the most common causes of non-Hodgkin's lymphoma (NHL). Some of these DLBCLs can have genetic mutations as well as protein overexpression. The genes involved are MYC, BCL-2 and BCL-6. These are very aggressive and do not respond well to standard chemotherapy regiment. Lymphomas usually show classic signs and symptoms but rarely can present with little or no symptoms or even mimic other disease processes. Here we will present a case where a spinal lymphoma mimicked a hematoma and the patient developed signs and symptoms only after mechanical fall and hitting his back.

SUBMITTER: Mufti M 

PROVIDER: S-EPMC7155832 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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A Great Mimicker in Thoracic Spine: Spinal Double Expressor Lymphoma.

Mufti Muhammad M   Nawab Khalid K   Mohammad Rabia R  

Journal of hematology 20180901 3


Diffuse large B-cell lymphoma (DLBCL) is one of the most common causes of non-Hodgkin's lymphoma (NHL). Some of these DLBCLs can have genetic mutations as well as protein overexpression. The genes involved are MYC, BCL-2 and BCL-6. These are very aggressive and do not respond well to standard chemotherapy regiment. Lymphomas usually show classic signs and symptoms but rarely can present with little or no symptoms or even mimic other disease processes. Here we will present a case where a spinal l  ...[more]

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