Ontology highlight
ABSTRACT:
SUBMITTER: Nanda S
PROVIDER: S-EPMC7155954 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Nanda Sumit S Das Ravi R Bhattacharjee Shatabdi S Cox Daniel N DN Ascoli Giorgio A GA
Brain structure & function 20171101 3
Pairing in vivo imaging and computational modeling of dendritic arborization (da) neurons from the fruit fly larva provides a unique window into neuronal growth and underlying molecular processes. We image, reconstruct, and analyze the morphology of wild-type, RNAi-silenced, and mutant da neurons. We then use local and global rule-based stochastic simulations to generate artificial arbors, and identify the parameters that statistically best approximate the real data. We observe structural homeos ...[more]