Ontology highlight
ABSTRACT:
SUBMITTER: Lacin H
PROVIDER: S-EPMC7156266 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Lacin Haluk H Williamson W Ryan WR Card Gwyneth M GM Skeath James B JB Truman James W JW
eLife 20200327
The <i>Drosophila</i> ventral nerve cord (VNC) is composed of thousands of neurons born from a set of individually identifiable stem cells. The VNC harbors neuronal circuits required to execute key behaviors, such as flying and walking. Leveraging the lineage-based functional organization of the VNC, we investigated the developmental and molecular basis of behavior by focusing on lineage-specific functions of the homeodomain transcription factor, Unc-4. We found that Unc-4 functions in lineage 1 ...[more]