Ontology highlight
ABSTRACT:
SUBMITTER: Fougner C
PROVIDER: S-EPMC7156396 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Fougner Christian C Bergholtz Helga H Norum Jens Henrik JH Sørlie Therese T
Nature communications 20200414 1
The claudin-low breast cancer subtype is defined by gene expression characteristics and encompasses a remarkably diverse range of breast tumors. Here, we investigate genomic, transcriptomic, and clinical features of claudin-low breast tumors. We show that claudin-low is not simply a subtype analogous to the intrinsic subtypes (basal-like, HER2-enriched, luminal A, luminal B and normal-like) as previously portrayed, but is a complex additional phenotype which may permeate breast tumors of various ...[more]