Ontology highlight
ABSTRACT:
SUBMITTER: Citro S
PROVIDER: S-EPMC7156594 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Citro Simona S Bellini Alice A Medda Alessandro A Sabatini Maria Elisa ME Tagliabue Marta M Chu Francesco F Chiocca Susanna S
Frontiers in cellular and infection microbiology 20200408
P63, and in particular the most expressed ΔNp63α isoform, seems to have a critical role in the outcome of head and neck cancer. Many studies have been conducted to assess the possible use of p63 as a prognostic marker in squamous cell carcinoma cancers, but the results are still not well-defined. Moreover, a clear relationship between the expression of ΔNp63α and the presence of high-risk HPV E6 and E7 oncoproteins has been delineated. Here we describe how ΔNp63α is mostly expressed in HPV-posit ...[more]