Ontology highlight
ABSTRACT:
SUBMITTER: Sidana S
PROVIDER: S-EPMC7156647 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Sidana Surbhi S Milani Paolo P Binder Moritz M Basset Marco M Tandon Nidhi N Foli Andrea A Dispenzieri Angela A Gertz Morie A MA Hayman Suzanne R SR Buadi Francis K FK Lacy Martha Q MQ Kapoor Prashant P Leung Nelson N Rajkumar S Vincent SV Merlini Giampaolo G Palladini Giovanni G Kumar Shaji K SK
Blood cancer journal 20200414 4
Newly diagnosed AL amyloidosis patients were evaluated to develop a model for early assessment of treatment benefit at 6 months, integrating both hematologic (HR) and organ response (OR) assessment (testing cohort, Mayo: n = 473; validation cohort, Pavia: n = 575). Multiple OR were assessed as follows: All OR (AOR): response in all organs, mixed OR (MOR): response in some organs, no OR (NOR)]. AOR rates at 6 months improved with deepening HR; complete response (CR; 38%, 35%), very good partial r ...[more]