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Effect of dietary fiber and threonine content on intestinal barrier function in pigs challenged with either systemic E. coli lipopolysaccharide or enteric Salmonella Typhimurium.


ABSTRACT: Background:The independent and interactive effects of dietary fiber (DF) and threonine (Thr) were investigated in growing pigs challenged with either systemic E. coli lipopolysaccharide (LPS) or enteric Salmonella Typhimurium (ST) to characterise their effect on intestinal barrier function. Results:In experiment 1, intestinal barrier function was assessed via oral lactulose and mannitol (L:M) gavage and fecal mucin analysis in pigs challenged with E. coli LPS and fed low fiber (LF) or high fiber (HF) diets with graded dietary Thr. Urinary lactulose recovery and L:M ratio increased (P?

SUBMITTER: Wellington MO 

PROVIDER: S-EPMC7158091 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature

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Effect of dietary fiber and threonine content on intestinal barrier function in pigs challenged with either systemic <i>E. coli</i> lipopolysaccharide or enteric <i>Salmonella</i> Typhimurium.

Wellington Michael O MO   Hamonic Kimberley K   Krone Jack E C JEC   Htoo John K JK   Van Kessel Andrew G AG   Columbus Daniel A DA  

Journal of animal science and biotechnology 20200415


<h4>Background</h4>The independent and interactive effects of dietary fiber (DF) and threonine (Thr) were investigated in growing pigs challenged with either systemic <i>E. coli</i> lipopolysaccharide (LPS) or enteric <i>Salmonella</i> Typhimurium (ST) to characterise their effect on intestinal barrier function.<h4>Results</h4>In experiment 1, intestinal barrier function was assessed via oral lactulose and mannitol (L:M) gavage and fecal mucin analysis in pigs challenged with <i>E. coli</i> LPS  ...[more]

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