Ontology highlight
ABSTRACT:
SUBMITTER: Mosher CP
PROVIDER: S-EPMC7159630 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Mosher Clayton P CP Wei Yina Y Kamiński Jan J Nandi Anirban A Mamelak Adam N AN Anastassiou Costas A CA Rutishauser Ueli U
Cell reports 20200301 10
Determining cell types is critical for understanding neural circuits but remains elusive in the living human brain. Current approaches discriminate units into putative cell classes using features of the extracellular action potential (EAP); in absence of ground truth data, this remains a problematic procedure. We find that EAPs in deep structures of the brain exhibit robust and systematic variability during the cardiac cycle. These cardiac-related features refine neural classification. We use th ...[more]