Ontology highlight
ABSTRACT:
SUBMITTER: Conibear AC
PROVIDER: S-EPMC7159640 | biostudies-literature | 2014 Sep
REPOSITORIES: biostudies-literature
Conibear Anne C AC Craik David J DJ
Angewandte Chemie (International ed. in English) 20140730 40
Cyclic peptides are found in a diverse range of organisms and are characterized by their stability and role in defense. Why is only one class of cyclic peptides found in mammals? Possibly we have not looked hard enough for them, or the technologies needed to identify them are not fully developed. We also do not yet understand their intriguing biosynthesis from two separate gene products. Addressing these challenges will require the application of chemical tools and insights from other classes of ...[more]