MicroRNA regulators of apoptosis in cancer.
Ontology highlight
ABSTRACT:
SUBMITTER: Bucur O
PROVIDER: S-EPMC7159826 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Publications
microRNA regulators of apoptosis in cancer.
Discoveries (Craiova, Romania) 20160401 1
This brief review summarizes our current knowledge on the microRNAs that regulate apoptosis machinery and are potentially involved in the dysregulation or deregulation of apoptosis, a well known hallmark of cancer. microRNAs are critical regulators of the most important cellular processes, including apoptosis. Expression of microRNAs is found to be dysregulated in many malignancies, leading to apoptosis inhibition in cancer, or resistance to current therapies. To date, there are over 80 microRNA ...[more]
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