Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia.
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ABSTRACT:
SUBMITTER: Villacampa P
PROVIDER: S-EPMC7160070 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Publications
Stabilization of myeloid-derived HIFs promotes vascular regeneration in retinal ischemia.
Villacampa Pilar P Liyanage Sidath E SE Klaska Izabela P IP Cristante Enrico E Menger Katja E KE Sampson Robert D RD Barlow Maeve M Abelleira-Hervas Laura L Duran Yanai Y Smith Alexander J AJ Ali Robin R RR Luhmann Ulrich F O UFO Bainbridge James W B JWB
Angiogenesis 20191003 2
The retinal vasculature is tightly organized in a structure that provides for the high metabolic demand of neurons while minimizing interference with incident light. The adverse impact of retinal vascular insufficiency is mitigated by adaptive vascular regeneration but exacerbated by pathological neovascularization. Aberrant growth of neovessels in the retina is responsible for impairment of sight in common blinding disorders including retinopathy of prematurity, proliferative diabetic retinopat ...[more]
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2010-05-31 | E-GEOD-20521 | biostudies-arrayexpress