Ontology highlight
ABSTRACT:
SUBMITTER: Kim M
PROVIDER: S-EPMC7160134 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Kim Miri M Park Hyo Eun HE Lee Si-Hyung SH Han Kyungdo K Lee Ji Hyun JH
Scientific reports 20200415 1
Although the pathogenesis of Alzheimer's disease (AD) is unclear, neuroinflammation appears to play a role in its development. Psoriasis is a chronic inflammatory skin disease that has recently been found to genetically overlap with AD. We aimed to investigate the risk of AD in patients with psoriasis. Subjects with psoriasis (n = 535,927) and age- and sex-matched controls without psoriasis (at a 5:1 ratio; n = 2,679,635) who underwent ≥3 health examinations between 2008 and 2014 were included, ...[more]