Ontology highlight
ABSTRACT:
SUBMITTER: Hou YS
PROVIDER: S-EPMC7160239 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Hou Yong-Sheng YS Wang Jing-Zhi JZ Shi Shuai S Han Ying Y Zhang Yue Y Zhi Ji-Xin JX Xu Chao C Li Fei-Feng FF Wang Gui-Yu GY Liu Shu-Lin SL
Bioscience reports 20200401 4
Congenital heart disease (CHD) is a group of anatomic malformations in the heart with high morbidity and mortality. The mammalian heart is a complex organ, the formation and development of which are strictly regulated and controlled by gene regulatory networks of many signaling pathways such as TGF-β. KAT2B is an important histone acetyltransferase epigenetic factor in the TGF-β signaling pathway, and alteration in the gene is associated with the etiology of cardiovascular diseases. The aim of t ...[more]