Ontology highlight
ABSTRACT:
SUBMITTER: Han X
PROVIDER: S-EPMC7160531 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Han Xu X Yang Jiong J Zeng Fanhong F Weng Jun J Zhang Yue Y Peng Qing Q Shen Li L Ding Shigang S Liu Kaiyu K Gao Yi Y
Molecular therapy oncolytics 20200330
Precisely identifying and killing tumor cells are diligent pursuits in oncotherapy. Synthesized gene circuits have emerged as an intelligent weapon to solve these problems. Gene circuits based on post-transcriptional regulation enable a faster response than systems based on transcriptional regulation, which requires transcription and translation, showing superior safety. In this study, synthetic-promoter-free gene circuits possessing two control layers were constructed to improve the specific re ...[more]