Ontology highlight
ABSTRACT:
SUBMITTER: Bustos AS
PROVIDER: S-EPMC7161950 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Bustos Atma-Sol AS Håkansson Andreas A Linares-Pastén Javier A JA Peñarrieta J Mauricio JM Nilsson Lars L
PloS one 20200416 4
Diets rich in flavonoids have been related with low obesity rates, which could be related with their potential to inhibit pancreatic lipase, the main enzyme of fat assimilation. Some flavonoids can aggregate in aqueous medium suggesting that the inhibition mechanism could occur on both molecular and colloidal levels. This study investigates the interaction of two flavonoid aggregates, quercetin and epigallocatechin gallate (EGCG), with pancreatic lipase under simplified intestinal conditions. Th ...[more]