Ontology highlight
ABSTRACT:
SUBMITTER: Liu C
PROVIDER: S-EPMC7164939 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Liu Congyue C Liu Wei W Wang Shufeng S Li Hongjia H Lv Zhilong Z Zhang Fa F Zhang Donghui D Teng Junlin J Zheng Tao T Li Donghai D Zhang Mingshu M Xu Pingyong P Gong Qihuang Q
Science advances 20200417 16
Super-resolution nanoscopy based on wide-field microscopic imaging provided high efficiency but limited resolution. Here, we demonstrate a general strategy to push its resolution down to ~50 nm, which is close to the range of single molecular localization microscopy, without sacrificing the wide-field imaging advantage. It is done by actively and simultaneously modulating the characteristic emission of each individual emitter at high density. This method is based on the principle of excited stat ...[more]