Ontology highlight
ABSTRACT:
SUBMITTER: de Vries ST
PROVIDER: S-EPMC7165141 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
de Vries Sieta T ST Denig Petra P Ekhart Corine C Mol Peter G M PGM van Puijenbroek Eugene P EP
Drug safety 20200501 5
<h4>Introduction</h4>In general, women more often experience metformin-associated adverse drug reactions (ADRs) than men.<h4>Objectives</h4>We aimed to assess whether sex differences in reported ADRs for metformin are observed at different times after initiation, and to explore their concurrence with sex differences in the dose of metformin over time. This may guide future studies in assessing the involved mechanisms of sex differences in metformin-associated ADRs and may guide sex-specific mana ...[more]