The Role of Pseudomonas aeruginosa Lipopolysaccharide in Bacterial Pathogenesis and Physiology.
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ABSTRACT:
SUBMITTER: Huszczynski SM
PROVIDER: S-EPMC7168646 | biostudies-literature | 2019 Dec
REPOSITORIES: biostudies-literature
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The Role of <i>Pseudomonas aeruginosa</i> Lipopolysaccharide in Bacterial Pathogenesis and Physiology.
Huszczynski Steven M SM Lam Joseph S JS Khursigara Cezar M CM
Pathogens (Basel, Switzerland) 20191219 1
The major constituent of the outer membrane of Gram-negative bacteria is lipopolysaccharide (LPS), which is comprised of lipid A, core oligosaccharide, and O antigen, which is a long polysaccharide chain extending into the extracellular environment. Due to the localization of LPS, it is a key molecule on the bacterial cell wall that is recognized by the host to deploy an immune defence in order to neutralize invading pathogens. However, LPS also promotes bacterial survival in a host environment ...[more]
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